Found 6 matching trials
Study of Miransertib (MK-7075) in Participants With PIK3CA-related Overgrowth Spectrum and Proteus Syndrome (MOSAIC) (MK-7075-002) PHASE1 This is an open label, Phase 1/2 study of oral miransertib (MK-7075) admini...
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Children's Hospital of Atlanta ( Site 0107)
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Dose Finding Trial of MK-7075 in Children and Adults With Proteus Syndrome PHASE1 Background:
Proteus syndrome (PS) is caused by a mutation in the AKT1 gene...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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A Study of the Safety and Tolerability in Participants With PIK3CA-related Overgrowth Spectrum or Proteus Syndrome Who Are Being Treated With Miransertib (MK-7075) in Other Studies (MK-7075-006) PHASE2 This is a study of the safety and tolerability of oral miransertib (MK-7075...
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Active Not Recruiting
Location
Children's Healthcare of Atlanta - Egleston Hospital ( Site 0107)
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Expanded Access to Provide ARQ 092 for the Treatment of Overgrowth Diseases and/or Vascular Anomalies N/A ARQ 092 is being investigated for patients with overgrowth diseases and/or ...
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No Longer Available
Location
Multiple Locations
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Open-label Phase 1b Study of ARQ 092 in Combination With Anastrozole PHASE1 An Open-label Phase 1b Study of ARQ 092 in Combination with other Antineopl...
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Multiple Locations
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Phase 1 Dose Escalation Study of ARQ 092 in Adult Subjects With Advanced Solid Tumors and Recurrent Malignant Lymphoma PHASE1 This is an open-label, Phase 1, dose escalation study of oral ARQ 092 admin...
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Multiple Locations
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